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Description

Gene expression pattern of alveolar macrophages of allergic asthmatics in comparison with control subjects - GSE22528

Purpose

The implication of alveolar macrophages (AM) in asthma, a Th2 disease, has not been well characterized. The purpose of this study was to better characterize alveolar macrophage phenotype of allergic asthmatic compared with normal subjects using genomic expression analyses.

Experimental Design

Alveolar macrophage samples from 5 allergic asthmatic subjects and 5 from control subjects (without allergy and asthma) were subjected to chip analysis (Affymetrix Human Genome U133A Array).

Experimental Variables

Asthma

Controls

5 non-asthmatic controls

Methods

Gene expression of AM isolated from bronchoalveolar lavage of 5 allergic asthamtic and 5 healthy control subjects were compared.

Platform Affymetrix HG-U133A
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GSE22528_v1.csv

GSE22528_v1.csv

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