The effect of a dexamethasone and a FK506 on the induction of chemokines in human mast cells - GSE15174new
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| Description | The effect of a dexamethasone and a FK506 on the induction of chemokines in human mast cells - GSE15174 |
| Purpose | The objective of this study was to comprehensively investigate FceRI-mediated chemokine induction in human mast cells and the effect of a corticosteroid (dexamethasone) and a calcineurin inhibitor (FK506). |
| Experimental Design | Human peripheral blood-derived mast cells were stimulated with anti-IgE antibody in the presence of dexamethasone or FK506. Gene expression profiles were evaluated using GeneChip Human Genome U133 plus 2.0 probe arrays (Affymetrix). |
| Experimental Variables | Stimulation with anti-IgE antibody in the presence of dexamethasone or FK506. |
| Controls | DMSO |
| Platform | Affymetrix HG-U133_Plus_2 |
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