Sample Set Annotation Tool: Gene expression profile of patients with moderate and severe chronic spontaneous urticaria

Study Design
Assay
Sample Info
Files
Info
Samples
Group Sets
Analysis

Purpose

The primary purpose of this study was to identify the most relevant genes expressed in the tissue and the blood samples from patients with moderate and severe chronic spontaneous urticaria (CSU). The knowledge of the gene profiling differences comparing wheal versus no-lesion skin in selected patients is a real and accurate approach to identify the genes expressed in the wheal developed in patients with CSU.

Hypothesis

Transcriptional profiling in CSU patients reveals implication of immunological genes.

Experimental Design

A total of 20 patients suffering of moderate and severe chronic spontaneous urticaria (CSU) and Chronic Idiopathic Urticaria (CIU) and 10 healthy control subjects were included.

Experimental Variables

CSU/CIU

Controls

10 healthy controls

Methods

Only patients showing active moderate to severe CSU during at least 3 months were included in the study. Skin and blood samples were taken from healthy and patients suffering from CSU/CIU.

Additional Information

Expected Samples:

61 Samples Loaded: 61

Species

Human (Homo sapiens)

Sample Source

Whole Blood , Skin

Disease

Chronic Spontaneous Urticaria

Treatment Protocol

Growth Protocol

Extraction Protocol

RNA was extracted using standard RNA extraction protocols (Trizol).

Storage Conditions

Sample Set Spreadsheet

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Samples Preview

Sample ID	tissue	group	Disease Status	ID
GSM1864752	skin	Healthy_skin	Healthy	B1
GSM1864753	non lesional skin	Patient_non lesional skin	Patient	A4
GSM1864754	non lesional skin	Patient_non lesional skin	Patient	A7
GSM1864755	wheal	Patient_wheal	Patient	A7
GSM1864756	non lesional skin	Patient_non lesional skin	Patient	A3

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File
GSE72542_v1.csv Sample Set Spreadsheet
GSE72542_v1.csv Sample Set Spreadsheet
GSE72542_v2.csv Sample Set Spreadsheet
GSE72542_v2.csv Sample Set Spreadsheet

Samples Viewer / Editor

All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.

Sample ID	Tissue	Group	Disease Status	ID
GSM1864752	skin	Healthy_skin	Healthy	B1
GSM1864753	non lesional skin	Patient_non lesional skin	Patient	A4
GSM1864754	non lesional skin	Patient_non lesional skin	Patient	A7
GSM1864755	wheal	Patient_wheal	Patient	A7
GSM1864756	non lesional skin	Patient_non lesional skin	Patient	A3
GSM1864757	skin	Healthy_skin	Healthy	B2
GSM1864758	non lesional skin	Patient_non lesional skin	Patient	A8
GSM1864759	wheal	Patient_wheal	Patient	A8
GSM1864760	non lesional skin	Patient_non lesional skin	Patient	A12
GSM1864761	skin	Healthy_skin	Healthy	B6
GSM1864762	non lesional skin	Patient_non lesional skin	Patient	A15
GSM1864763	wheal	Patient_wheal	Patient	A15
GSM1864764	non lesional skin	Patient_non lesional skin	Patient	A17
GSM1864765	wheal	Patient_wheal	Patient	A17
GSM1864766	skin	Healthy_skin	Healthy	B7
GSM1864767	non lesional skin	Patient_non lesional skin	Patient	A13
GSM1864768	non lesional skin	Patient_non lesional skin	Patient	A18
GSM1864769	wheal	Patient_wheal	Patient	A18
GSM1864770	skin	Healthy_skin	Healthy	B8
GSM1864771	non lesional skin	Patient_non lesional skin	Patient	A14
GSM1864772	skin	Healthy_skin	Healthy	B9
GSM1864773	skin	Healthy_skin	Healthy	A19
GSM1864774	wheal	Patient_wheal	Patient	A19
GSM1864775	wheal	Patient_wheal	Patient	A16
GSM1864776	non lesional skin	Patient_non lesional skin	Patient	A20
GSM1864777	wheal	Patient_wheal	Patient	A20
GSM1864778	non lesional skin	Patient_non lesional skin	Patient	A22
GSM1864779	wheal	Patient_wheal	Patient	A22
GSM1864780	non lesional skin	Patient_non lesional skin	Patient	XX
GSM1864781	wheal	Patient_wheal	Patient	XX
GSM1864782	skin	Healthy_skin	Healthy	B10
GSM1864783	blood	Healthy_blood	Healthy	B1
GSM1864784	blood	Patient_blood	Patient	A1
GSM1864785	blood	Healthy_blood	Healthy	B2
GSM1864786	blood	Patient_blood	Patient	A2
GSM1864787	blood	Patient_blood	Patient	A3
GSM1864788	blood	Healthy_blood	Healthy	B3
GSM1864789	blood	Patient_blood	Patient	A4
GSM1864790	blood	Patient_blood	Patient	A5
GSM1864791	blood	Patient_blood	Patient	A7
GSM1864792	blood	healthy_blood	healthy	B4
GSM1864793	blood	Patient_blood	Patient	A8
GSM1864794	blood	Healthy_blood	Healthy	B5
GSM1864795	blood	Healthy_blood	Healthy	B6
GSM1864796	blood	Patient_blood	Patient	A10
GSM1864797	blood	Patient_blood	Patient	A12
GSM1864798	blood	Patient_blood	Patient	A13
GSM1864799	blood	Healthy_blood	Healthy	B8
GSM1864800	blood	Patient_blood	Patient	A14
GSM1864801	blood	Patient_blood	Patient	A15
GSM1864802	blood	Patient_blood	Patient	A16
GSM1864803	blood	Patient_blood	Patient	A17
GSM1864804	blood	Patient_blood	Patient	A18
GSM1864805	blood	Healthy_blood	Healthy	B7
GSM1864806	blood	Patient_blood	Patient	A19
GSM1864807	blood	Patient_blood	Patient	A20
GSM1864808	blood	Healthy_blood	Healthy	B9
GSM1864809	blood	Patient_blood	Patient	A21
GSM1864810	blood	Patient_blood	Patient	A22
GSM1864811	blood	Patient_blood	Patient	XX
GSM1864812	blood	Healthy_blood	Healthy	B10

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SIDRA